Anti-Phospho-MAP3K7-S412 Polyclonal Antibody
产品名称: Anti-Phospho-MAP3K7-S412 Polyclonal Antibody
英文名称: CSCF;FMD2;MEKK7;TAK1;TGF1a
产品编号: K006194P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.