FITC标记的DNA损伤诱导转录蛋白4抗体
产品名称: FITC标记的DNA损伤诱导转录蛋白4抗体
英文名称: Anti-DDIT4/FITC
产品编号: HZ-4240R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-DDIT4/FITC Conjugated antibody
FITC标记的DNA损伤诱导转录蛋白4抗体
英文名称 | Anti-DDIT4/FITC |
中文名称 | FITC标记的DNA损伤诱导转录蛋白4抗体 |
别 名 | DDIT4; DDIT4_HUMAN; Dig2; DKFZp564O2071; DNA damage inducible transcript 4; DNA damage inducible transcript 4 protein; DNA damage-inducible transcript 4 protein; FLJ20500; HIF 1 responsive protein RTP801; HIF 1 responsive RTP801; HIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD 1; REDD-1; REDD1; RP11 442H21.1; RTP801. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 心血管 免疫学 染色质和核信号 新陈代谢 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DDIT4 (191-232aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death. Function: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death. Subcellular Location: Cytoplasm. Tissue Specificity: Broadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level). Similarity: Belongs to the DDIT4 family. Database links: Entrez Gene: 54541 Human Omim: 607729 Human SwissProt: Q9NX09 Human Unigene: 523012 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
通过调节TSC1-TSC2复合物上游和Akt1下游的Tor信号通路抑制细胞生长。促进神经元细胞死亡。