LCK polyclonal antibody
产品名称： LCK polyclonal antibody
英文名称： LCK polyclonal antibody
产品编号： PAB8803
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LCK.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human LCK.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 56
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody detects 56 KDa LCK. A low band ~25 KDa can also be detected, presumably to be a cleavage fragment of Lck.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.5-4 ug/mL)
Immunoprecipitation (20-25 ug/mL)
Immunohistochemistry (20-25 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3932
- Gene Name:
- LCK
- Gene Alias:
- YT16,p56lck,pp58lck
- Gene Description:
- lymphocyte-specific protein tyrosine kinase
- Omim ID:
- 153390
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
- Other Designations:
- T-lymphocyte specific protein tyrosine kinase p56lck,p56(LSTRA) protein-tyrosine kinase,protein tyrosine kinase,proto-oncogene tyrosine-protein kinase LCK
- Interactome
- Related Disease