PSMD2 Mouse Monoclonal Antibody [Clone ID: LBI1B5]-抗体-抗体-生物在线
安诺伦(北京)生物科技有限公司
PSMD2 Mouse Monoclonal Antibody [Clone ID: LBI1B5]

PSMD2 Mouse Monoclonal Antibody [Clone ID: LBI1B5]

商家询价

产品名称: PSMD2 Mouse Monoclonal Antibody [Clone ID: LBI1B5]

英文名称: PSMD2 Mouse Monoclonal Antibody [Clone ID: LBI1B5]

产品编号: AMM11529V

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围: WB 1:2000, IF 1:100

安诺伦(北京)生物科技有限公司
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别名:P97; RPN1; S2; TRAP2

产品概述:PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone LBI1B5

总结:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. [provided by RefSeq]