FITC标记的激肽释放酶5抗体
产品名称： FITC标记的激肽释放酶5抗体
英文名称： Anti-KLK5/FITC
产品编号： HZ-5869R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-KLK5/FITC Conjugated antibody
FITC标记的激肽释放酶5抗体
| 英文名称 | Anti-KLK5/FITC |
| 中文名称 | FITC标记的激肽释放酶5抗体 |
| 别 名 | HK5; Kallikrein 5; Kallikrein5; Kallikrein-5; Kallikrein L2; Kallikrein Like 2; Kallikrein related peptidase 5; KLK 5; KLKL 2; KLKL2; SCTE; Stratum Corneum Tryptic Enzyme. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 细胞粘附分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLK5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Kallikrein 5 was originally described from the skin as an enzyme involved in turnover of the stratum corneum, and later cloned from human EST libraries as a Kallikrein like enzyme. The skin is known to contain trypsin like and chymotrypsin like proteinases of 32 kDa and 25 kDa respectively, and these were determined to be hK5 and hK7. Kallikrein 5 is found is greatest abundance in the skin, and also in the brain, with lesser signal in the kidney, lung, mammary gland, and testis. Human breast milk is reported to contain high levels of Kallikrein 5. Less stringent PCR detects hK5 in many tissues, and analysis of cell lines by Western blot shows that many cell lines make hK5. Subunit: Interacts with SPINK9. Subcellular Location: Secreted. Tissue Specificity: Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. Similarity: Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 细胞外基质蛋白 |
激肽释放酶5最初从皮肤中描述为涉及角质层翻转的酶，并且后来从人类EST文库中克隆为激肽释放酶样酶。已知的皮肤含有胰蛋白酶样和糜蛋白酶样蛋白酶分别为32 kDa和25 kDa，并且这些被确定为HK5和HK7。激肽释放酶5被发现是皮肤中最大的丰度，也存在于大脑中，肾脏、肺、乳腺和睾丸中的信号较少。据报道，母乳中含有高水平的激肽释放酶5。不太严格的PCR检测HK5在许多组织中，并通过Western blot分析细胞系显示许多细胞系产生HK5。