MVP/LRP 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MVP/LRP 抗体

MVP/LRP 抗体

商家询价

产品名称： MVP/LRP 抗体

英文名称： MVP/LRP Antibody

产品编号： XY16478-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MVP/LRP 抗体

Applications
Tested Applications: ELISA, WB, IHC, IF, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in SH-SY5Y cells, A549 cells, HEK-293 cells, human brain tissue, mouse lung tissue, rat lung tissue, RAW264.7 cells
Positive IP detected in Mouse lung tissue
Positive IHC detected in Human lung tissue, human breast cancer tissue, human kidney tissue, human liver tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100
 MVP/LRP 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 16478-1-AP;SH-SY5Y cellsSH-SY5Y cells were subjected to SDS PAGE followed by western blot with 16478-1-AP(MVP antibody) at dilution of 1:500
  • 16478-1-AP;human lungImmunohistochemical of paraffin-embedded human lung using 16478-1-AP(MVP antibody) at dilution of 1:50 (under 40x lens)
  • 16478-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using MVP antibody 16478-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 16478-1-AP;mouse lung tissueIP Result of anti-MVP (IP:16478-1-AP, 4ug; Detection:16478-1-AP 1:500) with mouse lung tissue lysate 4000ug.
Product Information MVP/LRP 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: MVP/LRP fusion protein ag9593 Full Name: Major vault protein
Caculated Molecular
Weight:		 893aa,99 kDa Observed Molecular 
Weight:		 100-104kd
GenbankNo BC015623 GeneID: 9961
Symbol MVP Synonyms LRP, major vault protein, MVP, VAULT1
Background

Vaults are the largest cellular ribonuclear protein complexes with a hollow barrel-like structure, and have been associated with the MDR phenotype. Major vault protein (MVP) is the main component of vaults and is presumed to be involved in MDR. MVP is identical with the human lung resistance protein (LRP), known to be overexpressed in multiple chemotherapy resistance models [PMID:23083532]. MVP has been associated to resistance to radiotherapy [4], probably due to its role in preventing apoptosis by inhibiting the COP-1/p53 axis [PMID: 12894554, 15994960]. MVP/LRP 抗体

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