FITC标记的ANGEL1蛋白抗体
产品名称: FITC标记的ANGEL1蛋白抗体
英文名称: Anti-ANGEL1/FITC
产品编号: HZ-9741R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-ANGEL1/FITC Conjugated antibody
FITC标记的ANGEL1蛋白抗体
产品编号 | bs-9741R-FITC |
英文名称 | Anti-ANGEL1/FITC |
中文名称 | FITC标记的ANGEL1蛋白抗体 |
别 名 | ANGE1_HUMAN; ANGEL1; KIAA0759; mKIAA0759; Protein angel homolog 1; angel homolog 1; RGD1306238. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Cow, Horse, Sheep, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 75kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ANGEL1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
产品介绍 | background: ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies. Similarity: Belongs to the CCR4/nocturin family. Database links: Entrez Gene: 23357 Human Entrez Gene: 68737 Mouse SwissProt: Q9UNK9 Human SwissProt: Q8VCU0 Mouse Unigene: 497448 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
又名KIAA075,是属于CKR4蛋白家族的670个氨基酸。GANG1由位于人类14号染色体上的一个基因编码,包含约700个基因和1亿600万个碱基对,约占人类细胞DNA的3.5%。第14号染色体编码了早老素1(PSEN1)基因,这是与阿尔茨海默病发展相关的三个关键基因之一。SerpIA1基因位于14号染色体上,当有缺陷时,会导致遗传障碍?抗胰蛋白酶缺乏症。这种疾病的特点是严重的肺部并发症和肝功能不全。值得注意的是,第14号染色体上的免疫球蛋白重链基因座和通过与19号染色体编码蛋白BC3易位的融合可能与B细胞恶性肿瘤有关。