ACE2 polyclonal antibody
产品名称： ACE2 polyclonal antibody
英文名称： ACE2 polyclonal antibody
产品编号： PAB13444
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ACE2.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human ACE2.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- Anti-ACE2 has no cross response to ACE1.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.
Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, Somasundaran M, Sullivan JL, Luzuriaga K, Greenough TC, Choe H, Farzan M.Nature. 2003 Nov 27;426(6965):450-4.
- 2.
- Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM.Nature. 2002 Jun 20;417(6891):822-8.
- 3.
- A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.
Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S.Circ Res. 2000 Sep 1;87(5):E1-9.
- Entrez GeneID:
- 59272
- Protein Accession#:
- NP_068576
- Gene Name:
- ACE2
- Gene Alias:
- ACEH,DKFZp434A014
- Gene Description:
- angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- Omim ID:
- 300335
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq
- Other Designations:
- ACE-related carboxypeptidase,OTTHUMP00000022963,angiotensin I converting enzyme 2,angiotensin converting enzyme-like protein
- Gene Pathway
- Related Disease
- Arrhythmias, Cardiac
- Atrial Fibrillation
- Cardiomyopathy, Hypertrophic
- Cardiovascular Diseases
- Coronary Disease
- Death, Sudden, Cardiac
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Hypertrophy, Left Ventricular
- Hypotension, Orthostatic
- Intracranial Aneurysm
- Malaria, Cerebral
- Metabolic Syndrome X
- Sarcoidosis, Pulmonary