FITC标记的信号识别颗粒抗体
产品名称： FITC标记的信号识别颗粒抗体
英文名称： Anti-SRP68/FITC
产品编号： HZ-2381R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SRP68/FITC Conjugated antibody
FITC标记的信号识别颗粒抗体
| 英文名称 | Anti-SRP68/FITC |
| 中文名称 | FITC标记的信号识别颗粒抗体 |
| 别 名 | Signal recognition particle 68 kDa; Signal recognition particle subunit SRP68; Signal recognition particle 68 kDa protein; SRP 68; Srp68; SRP68_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 染色质和核信号 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 71kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SRP68 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Function: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Subunit: Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Subcellular Location: Cytoplasm. Nucleus, nucleolus. Similarity: Belongs to the SRP68 family. Database links: Entrez Gene: 6730 Human Entrez Gene: 217337 Mouse Entrez Gene: 363707 Rat Omim: 604858 Human SwissProt: Q9UHB9 Human SwissProt: Q8BMA6 Mouse Unigene: 514495 Human Unigene: 29655 Mouse Unigene: 68 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 信号识别颗粒(Signalrecognitionparticle,SRP)是介导蛋白识别转运其中普遍存在的机制之一,细胞内蛋白质的定向转移是蛋白质质量数量控制体系的一个重要环节,SRP对参与这一过程的功能基因和蛋白,尤其是蛋白的靶向输送机制的研究对揭示细胞的分化、代谢和病变具有重大的理论意义 |
信号识别颗粒装配在靶向粗内质网膜的分泌蛋白中具有关键性的作用。SRP68结合7S RNA，SRP72结合到该复合物随后。这种核糖核蛋白复合体可能直接与ER膜中的对接蛋白相互作用，并可能参与伸长阻滞功能。