Thymidylate Synthase (TYMS) Mouse Monoclonal Antibody [Clone ID: LBI5H8]
产品名称: Thymidylate Synthase (TYMS) Mouse Monoclonal Antibody [Clone ID: LBI5H8]
英文名称: Thymidylate Synthase (TYMS) Mouse Monoclonal Antibody [Clone ID: LBI5H8]
产品编号: AMM15126V
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB 1:2000, IHC 1:150
安诺伦(北京)生物科技有限公司
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别名:HST422; TMS; TS 产品概述:TYMS mouse monoclonal antibody, clone LBI5H8 总结:Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008]