别名：APO2; CD261; DR4; TRAILR-1; TRAILR1

产品概述：Carrier-free (BSA/glycerol-free) TNFRSF10A mouse monoclonal antibody, clone LBI11B12

总结：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]