FITC标记的环氧化物水解酶1抗体
产品名称: FITC标记的环氧化物水解酶1抗体
英文名称: Anti-Epoxide hydrolase 1/FITC
产品编号: HZ-14614R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Epoxide hydrolase 1/FITC Conjugated antibody
FITC标记的环氧化物水解酶1抗体
英文名称 | Anti-Epoxide hydrolase 1/FITC |
中文名称 | FITC标记的环氧化物水解酶1抗体 |
别 名 | EPHX 1; EPHX; EPHX1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal (xenobiotic); Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal (xenobiotic); HYEP_HUMAN; HYL1; MEH; Microsomal epoxide hydrolase. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 63kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Epoxide hydrolase 1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008] Function: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Found in liver. DISEASE: Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls. Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption. Similarity: Belongs to the peptidase S33 family. Database links: Entrez Gene: 2052 Human Entrez Gene: 535293 Cow Entrez Gene: 13849 Mouse Entrez Gene: 397639 Pig Entrez Gene: 25315 Rat Omim: 132810 Human SwissProt: P07099 Human SwissProt: Q9D379 Mouse SwissProt: P79381 Pig SwissProt: P07687 Rat Unigene: 89649 Human Unigene: 9075 Mouse Unigene: 3603 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
环氧化物水解酶是重要的生物转化酶,它把环氧化物从芳香族化合物的降解转化为可结合和从体内排泄的反式二氢二醇。环氧水解酶在环氧化物的活化和解毒中起作用。该基因的突变导致子痫前期、环氧水解酶缺乏或环氧酶水解酶活性增加。另一种编码这种蛋白质的剪接转录变体已被发现。(RefSeq,DEC 2008)