Anti-ALKBH1 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司--实验室产品
Anti-ALKBH1 Polyclonal Antibody

Anti-ALKBH1 Polyclonal Antibody

商家询价

产品名称: Anti-ALKBH1 Polyclonal Antibody

英文名称: ABH;ABH1;alkB;hABH;ALKBH

产品编号: K006862P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: null

使用范围: WB

北京索莱宝科技有限公司--实验室产品
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This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.