EBPL,EBPL蛋白抗体

产品编号HZ-14496R
英文名称EBPL
中文名称EBPL蛋白抗体
别 名Delta8-delta7 sterol isomerase related protein; EBPL; EBPL_HUMAN; EBRP; Emopamil binding protein like; Emopamil binding related protein; Emopamil-binding protein-like.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
EBPL,EBPL蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EBPL
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EBPL,EBPL蛋白抗体PubMedPubMed
产品介绍background:
EBPL is expressed as a homodimer with high levels found in liver, lung and kidney. As a transmembrane protein embedded on the endoplasmic reticulum, EBPL may function as a cholestenol delta-isomerase. The gene encoding EBPL is found on human chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Function:
Does not possess sterol isomerase activity and does not bind sigma ligands.

Subunit:
Homodimer.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed with highest levels in liver, lung and kidney.

Similarity:
Belongs to the EBP family.

Gene ID:
84650

EBPL,EBPL蛋白抗体Database links:
Entrez Gene: 84650 Human
SwissProt: Q9BY08 Human
Unigene: 433278 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.