分子量：Calculated MW: 7kDa/27kDa/31kDa
Observed MW: 32kDa

细胞定位：Nucleus

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.