FITC标记的碳酸酐酶11抗体
产品名称： FITC标记的碳酸酐酶11抗体
英文名称： Anti-CA XI/FITC
产品编号： HZ--8244R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CA XI/FITC Conjugated antibody
FITC标记的碳酸酐酶11抗体
| 产品编号 | bs-8244R-FITC |
| 英文名称 | Anti-CA XI/FITC |
| 中文名称 | FITC标记的碳酸酐酶11抗体 |
| 别 名 | CA-RP II; CA-RP XI; CA-XI; CA11; CAH11_HUMAN; Carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; CARP XI; CARP-2; CARP2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CA XI/Carbonic Anhydrase XI |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XI, also referred to as carbonic anhydrase-related protein 11 precursor (CA-RP XI) or carbonic anhydrase-related protein 2 (CA-RP II), is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA XI does not exhibit catalytic activity. It is expressed primarily in brain but is also found in spinal cord and thyroid. CA XI may play a role in brain development. Tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid. Function: Does not have a catalytic activity. Subcellular Location: Secreted (Potential). Tissue Specificity: Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid. Similarity: Belongs to the alpha-carbonic anhydrase family. Database links: UniProtKB/Swiss-Prot: O75493.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Carbonic anhydrases（CAS）是一大家族的锌金属酶的成员，负责催化二氧化碳的可逆水合作用。CAS在其分布和亚细胞定位方面表现出广泛的多样性。它们涉及多种生物过程，包括钙化、骨吸收、呼吸、酸碱平衡以及房水、唾液、胃液和脑脊液的形成。CAXI，也被称为碳酸酐酶相关蛋白11前体（CA-RP-XI）或碳酸酐酶相关蛋白2（CA-RP II），是缺乏carbonic anhydrase家族的成员，缺少两个对碳酸酐酶活性必需的三个Zn结合基序。因此，CaXI没有表现出催化活性。它主要在脑中表达，但也存在于脊髓和甲状腺中。CAXI可能在脑发育中发挥作用。
组织特异性：在大脑中大量表达，在脊髓和甲状腺中也有中度表达。