FITC标记的外致密纤维蛋白3B抗体
产品名称： FITC标记的外致密纤维蛋白3B抗体
英文名称： Anti-ODF3B/FITC
产品编号： HZ-9369R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-ODF3B/FITC Conjugated antibody
FITC标记的外致密纤维蛋白3B抗体
| 产品编号 | bs-9369R-FITC |
| 英文名称 | Anti-ODF3B/FITC |
| 中文名称 | FITC标记的外致密纤维蛋白3B抗体 |
| 别 名 | ODF3B; ODF3B_HUMAN; Odf3l3; Outer dense fiber of sperm tails 3B; Outer dense fiber protein 3-like protein 3; Outer dense fiber protein 3B. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 27kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ODF3B |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ODF3B, also known as ODF3L3 (outer dense fiber protein 3-like protein 3), is a 253 amino acid protein belonging to the ODF3 family. Existing as two isoforms produced by alternative splicing, ODF3B contains one DUF1309 repeat. The gene that encodes ODF3B maps to human chromosome 22, which contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. Similarity: Belongs to the ODF3 family. Contains 1 STPGR (Sperm-tail PG-rich) repeat. Database links: Entrez Gene: 440836 Human Entrez Gene: 70113 Mouse SwissProt: A8MYP8 Human SwissProt: Q5M8M2 Mouse Unigene: 531314 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ODF3B，又称ODF3L3（外致密纤维蛋白3样蛋白3），是属于ODF3家族的253氨基酸蛋白质。ODF3B作为一种DUF1309重复存在，作为选择性剪接产生的两种异构体存在。编码ODF3B的基因映射到人类22号染色体，包含500个以上的基因和大约4900万个碱基。作为第二个最小的人类染色体，22包含令人惊讶的各种有趣的基因。PelLAN McDeMID综合征，2型神经纤维瘤病和孤独症与22号染色体有关。在22号染色体上发现精神分裂症易感性位点，研究表明22q11缺失症状包括精神分裂症的高发病率。染色体9和5月22日间的易位导致了费城染色体的形成和随后产生的新型融合蛋白BCR-ABL，这是一种在多种类型的白血病中发现的强有力的细胞增殖激活剂。