EPS15 (N-term) Peptide
产品名称： EPS15 (N-term) Peptide
英文名称： EPS15 (N-term) Peptide
产品编号： P0967
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of EPS15.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human EPS15.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Molecular mechanism of NPF recognition by EH domains.
de Beer T, Hoofnagle AN, Enmon JL, Bowers RC, Yamabhai M, Kay BK, Overduin M.Nat Struct Biol. 2000 Nov;7(11):1018-22.
- 2.
- Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites.
Enmon JL, de Beer T, Overduin M.Biochemistry. 2000 Apr 18;39(15):4309-19.
- 3.
- Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain.
de Beer T, Carter RE, Lobel-Rice KE, Sorkin A, Overduin M.Science. 1998 Aug 28;281(5381):1357-60.
- Entrez GeneID:
- 2060
- Protein Accession#:
- EP15_HUMAN
- Gene Name:
- EPS15
- Gene Alias:
- AF-1P,AF1P,MLLT5
- Gene Description:
- epidermal growth factor receptor pathway substrate 15
- Omim ID:
- 600051
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- ALL1 fused gene from chromosome 1,OTTHUMP00000009896
- Gene Pathway
- Related Disease