FITC标记的同源三聚体锌指蛋白ZHX3抗体
产品名称： FITC标记的同源三聚体锌指蛋白ZHX3抗体
英文名称： Anti-ZHX3/FITC
产品编号： HZ-19232R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZHX3/FITC Conjugated antibody
FITC标记的同源三聚体锌指蛋白ZHX3抗体
| 英文名称 | Anti-ZHX3/FITC |
| 中文名称 | FITC标记的同源三聚体锌指蛋白ZHX3抗体 |
| 别 名 | KIAA0395; TIX1; Triple homeobox 1; Triple homeobox protein 1; ZHX 3; Zhx3; ZHX3_HUMAN; Zinc finger and homeodomain protein 3; Zinc fingers and homeoboxes protein 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 发育生物学 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 105kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZHX3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008] Function: Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed. High expression in kidney. Similarity: Belongs to the ZHX family. Contains 2 C2H2-type zinc fingers. Contains 5 homeobox DNA-binding domains. Database links: Entrez Gene: 23051 Human Omim: 609598 Human SwissProt: Q9H4I2 Human Unigene: 380133 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码锌指和同源盒（ZHX）基因家族的一个成员。该编码蛋白包含两个C2H2型锌指和五个同源域，并与自身或与锌指和同源框家族成员1形成二聚体。在核中，二聚蛋白与普遍存在的转录因子核因子-Y的A亚基相互作用，并可能作为转录因子发挥作用。