分子量：Calculated MW: 111kDa/115kDa
Observed MW: 80KDa

细胞定位：Mitochondrion inner membrane, Mitochondrion intermembrane space, Single-pass membrane protein

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结：This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.