FITC标记的唐氏综合征临界区域蛋白3抗体
产品名称： FITC标记的唐氏综合征临界区域蛋白3抗体
英文名称： Anti-DSCR3/FITC
产品编号： HZ-14430R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DSCR3/FITC Conjugated antibody
FITC标记的唐氏综合征临界区域蛋白3抗体
| 英文名称 | Anti-DSCR3/FITC |
| 中文名称 | FITC标记的唐氏综合征临界区域蛋白3抗体 |
| 别 名 | Down syndrome critical region protein 3; Down syndrome critical region protein A; Dscr3; DSCR3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DSCR3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008] Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the VPS26 family. Database links: Entrez Gene: 10311 Human Omim: 605298 Human SwissProt: O14972 Human Unigene: 369488 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
通过对部分三体21患者的分析，确定了21号染色体位于基因CBR和ERG之间的区域（CBR-ERG区域），在21q22.2上跨越2.5Mb。唐氏综合症的许多特征，包括形态学特征、低张力和精神发育迟滞，都与其发病机制密切相关。DsCR3（唐氏综合征关键区基因3）基因存在于该区域，推测含有八个外显子。DSCR3在大多数组织中均有表达。[ RefSeq，JUL 2008 ]