Phospho-PKC delta-S645 Rabbit pAb (APR29560N)
产品名称: Phospho-PKC delta-S645 Rabbit pAb (APR29560N)
英文名称: Phospho-PKC delta-S645 Rabbit pAb (APR29560N)
产品编号: APR29560N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 77kDa/80kDa Observed MW: 80kDa 细胞定位:Cell membrane, Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, Peripheral membrane protein, perinuclear region 稀释方法:WB 1:500 - 1:2000 总结:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.